1. Retina (Purdah) is like a photographic film on which image of the object seen by the eye is formed. Central portion of the retina which is visually most sensitive part is called the Macula.
2. ARMD is a specific disease in which as the name implies, there is a degeneration (progressive damage) of the macula with advancing age. Thus like cataract, ARMD also occurs in the old age.
3. Exact cause is unknown, probably ultraviolet rays of sunlight and heredity play a role. High blood pressure and smoking are other definite risk factors.
4. Two types of ARMD occur :
(i) Dry Type. Only pigment of macula is degenerated & it accounts for 80% of cases.
(ii) Wet Type. In which abnormal blood vessels get formed in the macula which may leak or bleed.
5. Wet type is more dangerous and damaging. Dry variety may sometimes progress to wet variety hence it should be kept under periodic checkup. These Patients must keep checking their vision with a special graphic chart (Amsler grid chart). This should be done regularly with each eye separately with near glasses on. Fixing eye at its central point, one has to look for any distortions, dark spots, etc. in the chart. Any new changes appearing on looking at the graph indicate fresh progression of disease.
6. No specific treatment is known for dry type. But recently in 1991, in a very large study in USA conducted for about 6 years, has shown beneficial results with intake of tablets containing vitamin-C, Vitamin-E, Beta-Carotene and Zinc. Advanced form of disease was thus prevented in many patients after regular intake of these tablets. All patients with ARMD must give up smoking, control their boood pressure well, eat plenty of fresh fruits and vegetables (especially green leafy vegetable like spinach, carrots, tomatoes, etc.
For wet type, fluorescein angiography (dye injection into vein of the hand to study blood vessels of the eye) is must to exactly localise the abnormal blood vessels and destroy it by laser rays or special injections into the eye (Anti-VEGF drugs like- Avastin, Lucentis). But whatever damage to vision has already been caused is irreversible. Only further damage can be controlled to some extent. This may have to be repeated multiple times.